Name | 5[-O-Dimethoxytrityl-N-benzoyl-desoxycytidine |
Synonyms | Bz-Dmt-dC DMT-dC-Bz 67219-55-0 N4-Bz-DMT-dC 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine 5[-O-Dimethoxytrityl-N-benzoyl-desoxycytidine N-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine 5'-O-(4,4'-Dimethoxytrityl)-N-benzoyl-2'-deoxycytidine N4-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxycytidine N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxycytidine 5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-(phenylcarbonyl)cytidine N-[1-[5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-hydroxy-oxolan-2-yl]-2-oxo-pyrimidin-4-yl]benzamide 1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxypentofuranosyl}-4-[(phenylcarbonyl)amino]pyrimidin-2(1H)-one N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-ribofuranosyl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide 4-(Benzoylamino)-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-beta-D-glycero-pentofuranosyl}pyrimidin-2(1H)-one 2(1H)-pyrimidinone, 4-(benzoylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-glycero-pentofuranosyl]- |
CAS | 67219-55-0 |
EINECS | 266-605-9 |
InChI | InChI=1/C37H35N3O7/c1-44-29-17-13-27(14-18-29)37(26-11-7-4-8-12-26,28-15-19-30(45-2)20-16-28)46-24-32-31(41)23-34(47-32)40-22-21-33(39-36(40)43)38-35(42)25-9-5-3-6-10-25/h3-22,31-32,34,41H,23-24H2,1-2H3,(H,38,39,42,43) |
Molecular Formula | C37H35N3O7 |
Molar Mass | 633.69 |
Density | 1.2234 (rough estimate) |
Melting Point | 119 °C |
Boling Point | 668.71°C (rough estimate) |
Water Solubility | 100μg/L at 20℃ |
Appearance | Crystalline Solid |
Color | White to Almost white |
BRN | 601627 |
pKa | 8.67±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 58 ° (C=1, MeOH) |
MDL | MFCD00010114 |
Use | Research tools for antiviral and antitumor research |
Risk Codes | R40 - Limited evidence of a carcinogenic effect R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R46 - May cause heritable genetic damage R45 - May cause cancer |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S53 - Avoid exposure - obtain special instructions before use. |
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 1 |
FLUKA BRAND F CODES | 1-3-10 |
HS Code | 29349990 |
LogP | 5.3 at 20℃ |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | N4-Benzoyl-5 '-O-(4,4'-dimethoxytrl)-2 '-deoxycytidine (5'-O-DMT-N4-Bz-dC) it can be used to synthesize oligodeoxynucleotides containing 3 '-S-thiophosphate (3'-PS) linkages and is a useful tool for probing enzyme-catalyzed cleavage processes in DNA. |